Carboxytherapy is the
transcutaneous administration of CO2 for therapeutic purposes
through intradermal or subcutaneous injections of medical gas using 30G or 32G
First discovered in France in 1932, in the medical spa of Royat. Doctors found that bathing in pools of carbon dioxide-rich water helped to speed up wound healing in peripheral arterial occlusive disease. CO2 was first used as a treatment of ischemic lower leg arterial diseases before medical treatments evolved to grafts, stents, and by-passes. Since 1930, hundreds of thousands of patients have undergone these procedures.
Where does Carboxytherapy act?
Microcirculation, reactivates the malfunctioning ones and increases the percentage of oxygen in the tissues, improving conditions such as swollen legs or various types of ulcer.
The skin, where it increases the percentage of oxygen in the tissues, improving wrinkles, stretch marks, circles under the eye, skin elasticity and inducing dermal rejuvenation.
The initial effects following CO2 injection are a strong vasodilatation, a
blood flow increase and a higher PO2 in the treated area. The Bohr effect describes
the tendency of haemoglobin to have less affinity for oxygen when the blood
concentration of CO2 is increased. This lower affinity leads the haemoglobin to
better release the oxygen in superficial tissues and muscles. CO2 is quickly
converted to bicarbonates and H+ acid in the presence of the carbonic anhydrase
Active arteriolar vasodilation through the
direct action of CO2 on vascular myocytes and through a mediated sympatholytic
mechanism with consequential blood flow speed increase, reopening of closed
capillaries thanks to the mechanical effect, reactivation of poorly functioning
capillaries and an increase in tissue oxygenation leading to an improvement in
conditions such as phlebostatic edemas and different ulcer types.
Increasing circulation, it improves skin
hydration and skin tone too
Tissue hyperoxygenation causes a metabolic
reactivation in all skin layers and stimulates fibroblast too. It is a bio
to tissue oxygenation, blood flow increase and the direct action on fibroblasts
(cells specialized in producing collagen and elastic fibres with consequent
thickening of the dermis) the skin looks firmer, toned and brighter.
The treatment is completely safe for the patient. Carbon dioxide is non-toxic and does not cause embolisms as it is perfectly compatible with the human body, which constantly produces and eliminates it through the venous system or through the lungs.
Oxygen ozone therapy is a medical practice carried out with a natural gas, ozone, free of side effects. It is used in the medical field for the treatment of numerous diseases. The concentrations of the oxygen-ozone mixture used are not dangerous to the human organism. Scientifically verified and approved routes of administration do not result in any adverse reaction; only inhaled administration can be toxic and irritating to the respiratory system.
Oxygen ozone therapy, as improperly called, is not clearly defined from the pharmacological point of view, despite its wide use. Its improper denomination has resulted in an improper assumption that the therapy is based on oxygen and ozone. The oxygen represents simply a carrier or a vehicle of the ozone molecule, and that its supposed oxygenating effects has only a minimal impact on the total biological action of ozone.